The International Max Planck Research School for Chemical and Molecular Biology (IMPRS-CMB) is a collaboration between the Max Planck Institute of Molecular Physiology and three universities, the Technical University Dortmund (TU Dortmund), the Ruhr University Bochum (RUB) and the University of Duisburg-Essen (DUE).

All four institutes are located in the Ruhr Metropolitan Area of Germany, an extremely vibrant and culturally interconnected region. The same spirit is reflected in the science of our program: research groups, with different and often complementary approaches, combine their efforts to study at the molecular level basic cell physiology.

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Dr. Andrey P. Antonchick

REACTION METHODOLOGY

Synthetic Chemistry
Chemical Biology

Organic, natural products, small molecules

Prof. Dr. Philippe I.H. Bastiaens

IMPACT OF DYNAMICS AND SPATIAL ORGANIZATION OF SIGNALLING MOLECULES/ACTIVITIES ON CELL PHENOTYPE

System Biology
Biophysical Chemistry

Cell Biology, Molecular Biology, Network Biology, Synthetic Biology, Theory of Complex Systems

Dr. Peter Bieling

CELL POLARITY AND MORPHOGENESIS


Dr. Alex Bird

CELLULAR REGULATION OF MICROTUBULE NETWORKS

Chromosomal Instability
Cell Division

cytoskeleton, genetics, biochemistry, cell cycle, genetic engineering

Prof. Dr. Dominik Boos

VERTEBRATE DNA REPLICATION


Dr. Andreas Brunschweiger

SYNTHESIS AND SCREENING OF DNA-ENCODED LIBRARIES


Dr. Leif Dehmelt

SPATIO-TEMPORAL REGULATION OF THE NEURONAL CYTOSKELETON


Prof. Dr. Michael Ehrmann

PROTEIN QUALITY CONTROL


Prof. Dr. Ralf Erdmann

PROTEIN IMPORT INTO PEROXISOMES


Prof. Dr. Klaus Gerwert

CHAIR OF BIOPHYSICS AT RUHR UNIVERSITY BOCHUM


Dr. Sven Hennig

THERAPEUTIC TRANSCRIPTOME MODIFICATIONS


Matías Hernández, PhD

CELL-CELL MEMBRANE FUSION

Molecular Biology
Cell Fusion

molecular machines, yeast genetics, biochemical assays, fluorescence microscopy

Prof. Dr. Markus Kaiser

ELUCIDATION OF THE MODE-OF-ACTION OF NATURAL PRODUCTS


Prof. Dr. Stefan M. Kast

THEORETICAL PHYSICAL CHEMISTRY

Small Molecule Modulators
Protein Structure and Funtion

MODELING AND SIMULATIONS, COMPUTATIONAL CHEMISTRY, PHYSICAL CHEMISTRY, DRUG DEVELOPMENT

Dr. habil. Aneta Koseska

CELLULAR COGNITION/DYNAMIC ORGANIZATION PRINCIPLES OF LIVING SYSTEMS


Prof. Dr. Nils Metzler-Nolte

MEDICINAL INORGANIC CHEMISTRY


Prof. Dr. Hemmo Meyer

CELLULAR HOMEOSTASIS, PROLIFERATION AND STRESS RESPONSES


Prof. Dr. Andrea Musacchio

CELL DIVISION IN VITRO AND IN VIVO


Dr. Heinz Neumann

INVESTIGATION OF CHROMATIN DYNAMICS WITH AN EXPANDED GENETIC CODE


Prof. Dr. Stefan Raunser

STRUCTURAL BIOCHEMISTRY

Structural Biology

Cytoskeleton, Host-Pathogen Interaction, Protein Structure and Function, Cryo-Electron Microscopy, Image Processing, X-ray crystallography

Dr. Dennis Schade

STEM CELLS: MEDICINAL CHEMISTRY FOR CARDIAC REGENERATION


Dr. Christian Schröter

CELL COMMUNICATION AND FATE DECISIONS

Stem Cell Biology
Cell Signalling

cell fate decisions, intercellular communication, pattern formation, live cell imaging, Systems biology

Prof Dr. Frank Schulz

CHEMISTRY AND BIOCHEMISTRY OF NATURAL PRODUCTS


Prof. Dr. Daniel Summerer

NUCLEIC ACID CHEMICAL BIOLOGY


Prof. Dr. Jörg Tatzelt

BIOCHEMISTRY OF NEURODEGENERATIVE DISEASES


Dr. Gerben Vader

CONTROL OF MEIOTIC CHROMOSOME FRAGMENTATION


Dr. Ingrid Vetter

CRYSTALLOGRAPHY


Prof. Dr. Herbert Waldmann

DEPARTMENT OF CHEMICAL BIOLOGY

Chemical Biology
Synthetic Chemistry

biochemistry, cell biology, computational chemistry, medicinal chemistry

Prof. Dr. Stefan Westermann

KINETOCHORES AND THE MICROTUBULE CYTOSKELETON


Prof. Dr. Konstanze F. Winklhofer

MOLECULAR CELL BIOLOGY


Prof. Dr. Roland Winter

BIOPHYSICAL CHEMISTRY/MEMBRANE BIOPHYSICS

Membrane Dynamics
Conformational Dynamics

HIGH PRESSURE TECHNIQUES, TIME RESOLVED SPECTROSCOPY, FLUORESCENCE MICROSCOPY, ATOMIC-FORCE MICROSCOPY, X-RAY and NEUTRON SCATTERING

Prof. Dr. Yaowen Wu

MEMBRANE TRAFFICKING AND AUTOPHAGY

Chemical Biology
Cell Biology

biochemistry, chemical and genetic perturbations, protein structure and function, biosensors, optogenetics